Recent comments in /f/askscience

thecooliestone t1_j97qxei wrote

No.

Even if they could, how could they tell if it was you smoking or second hand smoke?

I have lung issues from second hand smoke and every time I go to a new doctor they ask if I smoke and kind of don't believe me until I say both my parents did my entire childhood in the house and in cars.

Maybe your parents smoked. Maybe a spouse does. Maybe you just worked in a smoking bar. Who could tell?

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Tongalaxy t1_j97ovmc wrote

The body's cyclical fever response is not fully understood but is thought to be a result of the body's attempt to fight off the infection or injury. The fever response may help to activate the immune system and inhibit the growth and reproduction of some pathogens.

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redligand t1_j97jyah wrote

It is a lot, yes. But they still have a bit of a point. In absolute terms lung cancer isn't hugely common in smokers. About 1 in 10. So you're still somewhat unlikely to get lung cancer as a smoker. Although you're massively more likely to get it compared with someone who has never smoked. So it's a huge relative risk but a somewhat low absolute risk. As an individual even if you smoke the odds are still in your favour wrt lung cancer. Of course, with smoking there is a bunch of other things that can kill you before you get the chance to win the prize of lung cancer. So that has to be considered too.

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Snoo16319 t1_j97g3yn wrote

Lung doc here. Not all obstruction reduces DLCO, DLCO is traditionally preserved in non-remodeled asthma.

That said, as a lung cancer researcher, KRAS mutation is much much more common in those who have smoked (not exclusive though). In modern practice, we are doing more assessment of tumor mutational burden and TMB is a lot higher in those who have smoked. Lastly, some subtypes, namely small cell and squamous cell, are almost unheard of in those who have never smoked.

Establishing causation in science is hard, and we observe changes correlated with tobacco use, but as they say, correlation and causation are not the same. We know epidemiologically and through cell and animal models the effects of tobacco smoke on DNA and cell growth, but in an individual, it would be close to impossible to establish exact causation.

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rational_american t1_j97epu7 wrote

Where would this be? That sounds like variations in temperature are causing condensation. I have lived on a literal island in the ocean, 500 meters from the pounding waves, and have had my salt clump a bit, but never dissolve itself into salt water in the container, even though dew and condensation was on everything at least some part of almost every day.

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Octavus t1_j97d735 wrote

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Bax_Cadarn t1_j97cf64 wrote

I'm studying for a big exam and basically every disease, restrictive or obturative, lowers DLCO lol. (Barring alveolar hemorrhage). Not just COPD or smoking-related diseases like DIP.

By identifying cells from BF or EBUS or biopsies, You mean like looking for macrofages loaded with soot?

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darthaxolotl t1_j979ai4 wrote

Wow, wow, wow -- 10-15% of smokers get lung cancer that is A LOT. Yes, most of them end up dying of vascular or lung disease other than cancer (and probably some of those that died of heart attacks also related to their smoking would have gone on to get lung cancer). In non-smokers the number of primary lung cancers is <<1%.

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