Recent comments in /f/askscience

nicholsz t1_j8td4oa wrote

Yes, blood is toxic to neurons. We have a blood-brain barrier that only lets some things through (either passively if they're small enough like oxygen or alcohol, or actively for bigger molecules).

The brain sits in cerebrospinal fluid (CSF) rather than blood.

As for the actual mechanisms that blood will damage the brain -- first, if you've got a brain bleed, it'll increase intracranial pressure and make it harder for new oxygenated blood to get in, which will kill your neurons from simply lack of oxygen. Second, even a small bleed will kill neurons, because things like the sodium concentration in your CSF will get messed up, and then when the blood dies in your brain it'll leave behind a bunch of iron from hemoglobin which will also kill your neurons.

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Chemomechanics t1_j8snwzw wrote

The medium plays a part in the momentum transfer, yes.

The net force on a spherical body isn't zero for a single beam because the beam changes shape moving through it, so the refractive details are different on either side.

But for two counterpropagating beams, which is what I used, the left–right forces do balance out, leaving an internal tensile load that stretches a compliant medium. You don't notice this in everyday situations with macroscale objects because they're stiff and the light is weak.

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CrateDane t1_j8sm4jy wrote

Neurons, especially in the CNS (brain/spinal cord), are quite sensitive, and are usually kept in a sheltered environment separated from the blood by the blood-brain barrier. Astrocytes and other glial cells provide a controlled environment for the neurons. They do take nutrients from the blood, but they act as a filter to only let through the right things and in the concentrations that neurons prefer.

Even in other tissues, blood isn't usually supposed to leave the blood vessels, and can cause trouble if it does. Perhaps the easiest to understand is coagulation - if everything's clotted up, that will disrupt whatever else is supposed to be happening in that tissue. There are also immune molecules which tend to get activated and cause inflammation when outside blood vessels. Inflammation generally interferes with regular tissue function, and CNS neurons are particularly sensitive to it.

Blood also contains higher concentrations of stuff like iron that would damage neurons.

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CrustalTrudger t1_j8s5ruo wrote

Yep, it's even got a name, Maui Nui and included Kaho‘olawe as well (and some bits that are no longer islands). The general concept has been around for a while (e.g., Stearns & Macdonald, 1942) and there's been a variety of efforts to "reconstruct" what this island would have looked like (e.g., Price & Fisk, 2004). In detail, the Price and Fisk reconstruction suggests that Maui Nui at its maximum extent was actually larger than the "Big" Island is today.

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