Recent comments in /f/IAmA

EzekielNOR OP t1_iwzzlvz wrote

I will start a bit early with answering - may it give some ideas for questions :)

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I think that it's closing in on that point in some cases. If you take a look at Megascans assets - you need to take a real hard look to realise it is computer graphics.

It may take some time to get at that level in your "average game" - but I am confident it will happen.

Another interesting thing with things like VR: "Most" people lose a sense of where they are within 30-60 seconds. Users experience a very high degree of immersion using VR. No one will forget that they have a VR headset on them, but it does show us that we can trick the brain relatively easily. In fact - we see a very real, and relatively powerful painkilling effect using VR on patients with chronic, or even acute pain.

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irishnewf86 t1_iwzozd3 wrote

thanks for validating my comment :)

You were so triggered by a harmless comment that you had to make up a comment about my alleged "divisive" comment history!

The only posts of mine that have been massively downvoted are the ones where I point out that injecting a carcinogen into a living organ for narcissistic aesthetic purposes is a stupid thing to do.

But hey, if injecting printer ink into living cells is your thing, fill your boots, moron.

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spectaphile t1_iwz1m0i wrote

Why would you expect a fertility specialist to be of any use in learning how to advocate for sterilization? They literally do the opposite of what you are asking after.

Seems like you are asking this question just to troll - "I've heard..." Not you've experienced, but you've "heard". As someone who did seek sterilization and was declined, the answer, as with any other medical issue, is to find a doctor willing to treat you in the manner in which you wish to be treated. Sometimes that's easier than others. But in all of my search, I never thought a fertility specialist was the correct resource.

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SpankAPlankton t1_iwy3du5 wrote

Why do human females have menstrual periods when most female animals simply reabsorb their uterine lining if they don't become pregnant? I can't think of any evolutionary advantage to this often incapacitating process. Back in the prehistoric days, it would've hindered many women's ability to gather food, run from dangerous situations, take care of other offspring, and other things they'd need to do to survive.

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DrJosephDavisDO OP t1_iwxqi3s wrote

Hi @strawberrywine5880,

Many of my patients choose to do genetic testing if embryos (PGT) for several reasons. For patients over 37, the odds of an embryo being genetically abnormal exceeds the odds of a normal embryo and this can mean lower pregnancy rates and a higher miscarriage rate. For others who are younger, especially those with PCOS or unexplained sub fertility, they often have a large number of embryos and use PGT as a tool to identify the chromosomally optimal ones.

Like all tests though, PGT is not 100% accurate. This can mean “normal” embryos may be discarded if the test inaccurately shows they don’t have the right number of chromosomes. There is also additional cost to PGT which is a factor.

Many patients I’ve spoken to have balanced the cost of PGT ($2000 in my practice) with the cost of a failed frozen embryo transfer (also $2000) and given the higher pregnancy rate and lower miscarriage rate with PGT tested embryos have stated they feel the cost is worth the benefit.

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DrJosephDavisDO OP t1_iwxpahf wrote

Hi @rosegolddragon,

There are some risks of pregnancy as we approach our later 30s and 40s but a lot depends on your overall health status (such as high blood pressure, etc). The other risks we think of related to pregnancy over 35 are risks of genetic problems in the baby. The risk of having a baby with Down’s Syndrome for example is 1/1000 roughly at age 30 and is closer to 1/350 by age 35 and 1/100 by age 40. An unfortunate corollary to the increased chromosomal abnormalities is an increased chance of miscarriage. These risks related to the baby don’t seem to be reduced with diet or lifestyle but can be tested for using PGT.

If you have other medical conditions like high blood pressure or diabetes, lifestyle and diet can in some cases help reduce the risks associated with those conditions. Hope that helps!

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DrJosephDavisDO OP t1_iwxobmf wrote

Good follow up question! See my reply above but yes, hCG worsens OHSS. This is not only from an hCG trigger but also from a fresh transfer that implants and begins making hCG. This is the theory behind using agonist triggers and avoiding fresh transfers when OHSS is suspected.

Unfortunately not all OHSS can be avoided. We can just use certain approaches to lessen the duration of the OHSS and reduce the risk of worsening symptoms.

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DrJosephDavisDO OP t1_iwxnynk wrote

Great question. OHSS does get worse shortly after trigger especially with an hCG trigger (vs an agonist trigger). The symptoms peak as you rightly said 3-7 days after trigger. The benefit of freezing embryo rather than fresh transfer is the reduce the severity of the OHSS while it resolves. I typically use agonist triggers and plan to freeze if I see any risks or signs of OHSS. Even in the best of situations however OHSS can still happen. I believe the most important way to address OHSS is to have an open discussion about the signs and symptoms and make a plan with my patient about how to proceed. That being said, I do very few fresh transfers and have seen very few cases of severe OHSS since moving to that approach.

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doingallthething t1_iwx4w26 wrote

Here's a good medically reviewed article that might have some good insight for you. Overall, there's a lot of things people think impact fertility but ultimately don't really have any true weight behind them. Being healthy and making healthy decisions is the best thing you can do! https://www.fertilitywise.com/research/getting-pregnant-via-sex

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doingallthething t1_iwx3w2t wrote

I really like this article (and heck-the whole site because it's medically reviewed, not just someone's biased opinion, and the articles tend to be easier to read than ASRM or other medical articles) and thought you might find it helpful. Even though it's meant for getting pregnant via sex, it's got some good points about "how to optimize fertility" that you might find helpful! https://www.fertilitywise.com/research/getting-pregnant-via-sex

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