You read my mind! It was the same for me. They were monitoring and were ready to freeze embryos and switch to an FET instead of fresh transfer, but I was already there... I know sometimes implantation can trigger symptoms to get worse, so maybe that's what he's implying??

Here is a medically reviewed article that you could share with your sister. Also, a lot of people with genetic concerns opt to use donor eggs or donor embryos, so they don't have to worry about passing that genetic concern on. But this article is a good place to start! https://www.fertilitywise.com/research/preimplantation-genetic-testing-pgt

What’s your live birth rate? In the end, that the most important number.

What software do you use for post-production and cutting process?

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If the overstimulation happened during the egg retrieval cycle how do you suggest that not doing a fresh transfer is an option to prevent it? I had ohss already by the time of my egg retrieval, and my doctor told me (accurately to my experience and literature) that ohss symptoms peak in days 3-7 from the procedure. So while sure maybe the transition to fresh transfer would make it worse, surely that doesn’t actually have any prevention success for OHSS that has already begun. OP sounds like she’s doing a FET already anyway.

Ha! That's awesome. Maybe they saw this thread and now I have an excuse to go there in the best future

Well, currently sitting and red chili and I see they have finally painted it. 😝

Cool Thanks, just nice to get a straight answer to a stupid question that the stupid internet puts in my head from time to time.

Thank you for being here! I'm 34 and I'm looking at having my second child in a couple years. I heard the risk of health issues goes up after 35. Is this a significant risk (are we talking single digit odds or double?). Does IVF lower these risks? Are their natural ways such as diet that lower these risks? Thank you in advance.

What are your thoughts on genetic testing of embryos?

If a baby's head isn't going to fit through the pelvis and require an emergency c-section, is there any way to know this before it happens in the moment?

Hi - thank you for doing this AMA! What advice regarding protocol would you give someone with a normal AMH/AFC but elevated FSH (10.06) Is there any indication that elevated FSH will mean poor egg quality?

Hello, I was misdiagnosed with PCOS when I had a far more serious illness. I am currently battling cushings disease. My endocrinologist has said he does not see a resolvable issue in regard to me later starting a family. I am skeptical of this.

What tests should I request in regard to fertility and what are the risks post cushings in regard to pregnancy?

Thank you

Hi Dr! I'm a postgrad student doing clinical embryology and have a question about PLCzeta. Can we say it is the only factor that contributes to oocyte activation? If not, what other factors can we consider? If yes, to what extent?

Hi u/Harlan2114

Thanks for the question. The 2 main types of protocols are agonist and antagonist. There is data suggesting longer agonist suppression can help with early follicle growth, but this can also over suppress some follicles. The estrogen priming protocol is a nice blend of suppression with the added advantage of antagonist. I see a lot of patients with a similar situation. If you want to reach out to my office, we could set up a consultation to talk about your specific case. (email contact@caymanIVF.com)

Hi u/SongBird2007

I am sorry to hear about your situation. Many medical conditions can have an impact on fertility, and it is often hard to find a balance. PCOS and insulin resistance are both very commonly linked to fertility problems. You ideally want to make sure you are working with a doctor you feel is addressing your needs in a supportive and productive way. Also be sure you are taking time for yourself!

Hi u/Iamatworkgoaway,

I haven't seen this in my clinic. That's not to say it isn't being asked elsewhere.

Hello! Thank you so much for being here. What IVF retrieval protocol would you suggest for someone with endometriosis and who has the issue of dominant follicles? I have poor egg quality and have a hard time making blastocysts. Thank you so much!

Hi u/HaworthiaRYou

Great question. There are many ways to reduce OHSS, one of which is freezing the embryos and planning for an FET. This is a very effective option. In nearly everyone who is experiencing OHSS, the symptoms are gone by the time of your period. That being said, most doctors will still want to assess you before starting the FET cycle just to be sure.

Thank you for your thoughtfulness and support in doing this AMA. It is greatly appreciated!

I’ve been to many doctors about plenty of my fertility issues. I didn’t go initially because—what woman wouldn’t want less periods (and pain monthly). Not until I got older I started to understand the negative sides of that. Is there any way to narrow down if my disorders are causing each other or they’re unrelated and just stack?

Diagnosis: PCOS, Low thyroid function, insulin resistance, sleep apnea, and whatever I can’t think of.

It’s like every year the doctor just tacks on something else I have that’s still causing me to have fertility issues….

ERA (endometrial receptivity assay) for those who aren't familiar is a tool designed to determine the best time of the cycle to transfer a frozen embryo after IVF. The studies on ERA have sown benefit in some patients if they have had multiple failed embryo transfers. In my clinic, I specialize in PGT single embryo transfers. Our current pregnancy rate using PGT is >85% per embryo transfer and as such I haven't found much of an improvement using ERA for my patients. I would recommend anyone considering having an ERA, ask your clinic how much of an improvement they have seen using the ERA so you can make the most informed decision.

Is there any truth to the rumors that people are looking for non covid or vax sperm/eggs?

My pleasure!

Does the risk of OHSS decline or end once period resumes after an embryo retrieval (and will go under FET protocol with oral intake of Estrace)?