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cepheid22 t1_j5mr9ij wrote

That is very interesting as schizophrenia is linked with nicotine use and ADHD. The vast majority of schizophrenics smoke at some time in their lives, many citing that it helps with symptoms though the research is inconclusive. Schizophrenia and ADHD have high comorbidity rates. Not to mention that psychosis can be a symptom of Parkinson's. Ah, that wiley dopamine!

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stokeitup t1_j5mnyft wrote

I have seen nicotine inhalers sold over the counter in Canada (Amazon search) yet they are not sold in the US, from what I can tell. Are these inhalers effective and if so, do you know why they are not sold in the US?

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uglyman1717 t1_j5lw54q wrote

Hi there thank you for answer any and all questions. My question is regarding cigar smoking. I enjoy on average 3-4 cigars a month, summer time maybe closer to 7-8 a month. Obviously with any type of smoking I understand that I have a higher chance of lung cancer than not smoking at all, but what type of long term negatives should I be aware of and how dangerous is it to have on average 3-4 cigars a month? Thank you

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BrownNWG OP t1_j5lmzz0 wrote

>When comparing cigarettes to vaping, how to you do an apples to apples comparison for qty and nicotine levels. For and example a Marlboro red equals X MG of nicotine per cigarette. How may mil of e-juice at what nic level would be equal?
>
>This would be good to know if you are using vaping to quit and lower your nic dosage.

This is a question our research field struggles with because nicotine content does not equal what gets into the blood. Part of the difficulty is that there are differences between people and products (see our response here: https://www.reddit.com/r/IAmA/comments/10jkffc/comment/j5licye/?utm_source=share&utm_medium=web2x&context=3). The best research on this looks at the actual concentration of nicotine that gets into the bloodstream. For example, the nicotine salts in e-liquid and their concentration were closely designed to match the nicotine delivery of a cigarette (see this chart from the patent filing from Pax labs, the company that spun off JUUL: https://patentimages.storage.googleapis.com/11/28/4a/9dc40046044330/US09215895-20151222-D00004.png).

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BrownNWG OP t1_j5lkfn0 wrote

>Is it known what percentage of cravings a person has in a typical day for tobacco is the result of actual withdrawal vs habit?

This is a great research question! It can be helpful to think about craving, withdrawal and habit as “motives” for smoking (in other words: what drives people to use). Some other motives include: automaticity (smoking mindlessly), coping with negative emotions, affiliative attachment (seeing cigarettes as a ‘friend’), among others. There is a lot of research looking at how these motives relate to each other and to smoking (for example: https://journals.sagepub.com/doi/full/10.1177/2167702620978614) but there is still a lot of work to be done.

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675triumphtriple t1_j5lkfj3 wrote

When comparing cigarettes to vaping, how to you do an apples to apples comparison for qty and nicotine levels. For and example a Marlboro red equals X MG of nicotine per cigarette. How may mil of e-juice at what nic level would be equal?
This would be good to know if you are using vaping to quit and lower your nic dosage.

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BrownNWG OP t1_j5licye wrote

>What is considered a low dose?

This is a tough question. It depends on the product. Different products are absorbed into the bloodstream differently. For example, much of the nicotine in smoking and vaping rapidly enters the bloodstream while the same dose of nicotine in a skin patch is absorbed over a few hours. In other words, the same dose of nicotine from different products is absorbed differently and impacts the user differently. A "low dose" also varies by person depending on how much they have been using.

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